Defensin BmKDfsin4

General Information


DRACP ID  DRACP04012

Peptide Name   Defensin BmKDfsin4

Sequence  GFGCPFNQGQCHKHCQSIRRRGGYCDGFLKTRCVCYR

Sequence Length  37

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Native peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antiviral



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C181H278N62O48S6

Absent amino acids  AEMW

Common amino acids  CG

Mass  492526

Pl  9.18

Basic residues  9

Acidic residues  1

Hydrophobic residues  6

Net charge  8

Boman Index  -9711

Hydrophobicity  -71.35

Aliphatic Index  28.92

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  3355

Absorbance 280nm  93.19

Polar residues  17

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 27128943

Title  A Scorpion Defensin BmKDfsin4 Inhibits Hepatitis B Virus Replication in Vitro

Doi Not available

Year  2016

Literature 2

Pubmed ID 26817841

Title  Scorpion Potassium Channel-blocking Defensin Highlights a Functional Link with Neurotoxin

Doi Not available

Year  2016

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  15563

DRACP is developed by Dr.Zheng's team.