Ocellatin-3N
General Information
DRACP ID DRACP04031
Peptide Name Ocellatin-3N
Sequence GIFDVLKNLAKGVITSLAS
Sequence Length 19
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C89H152N22O26
Absent amino acids CEHMPQRWY
Common amino acids L
Mass 226758
Pl 9.54
Basic residues 2
Acidic residues 1
Hydrophobic residues 10
Net charge 1
Boman Index 533
Hydrophobicity 91.05
Aliphatic Index 143.68
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 6
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 36426386
Title Antimicrobial, cytotoxic, and insulin-releasing activities of the amphibian host-defense peptide ocellatin-3N and its L-lysine-substituted analogs
Doi Not available
Year 2022
Literature 2
Pubmed ID 33092132
Title Peptidomic Analysis of Skin Secretions of the Caribbean Frogs Leptodactylus insularum and Leptodactylus nesiotus (Leptodactylidae) Identifies an Ocellatin with Broad
Doi Not available
Year 2020
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 16392