DIM-LF11-322

General Information


DRACP ID  DRACP04054

Peptide Name   DIM-LF11-322

Sequence  PFWRIRIRRPFWRIRIRR

Sequence Length  18

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C122H194N44O19

Absent amino acids  ACDEGHKLMNQSTVY

Common amino acids  R

Mass  288454

Pl  13.35

Basic residues  8

Acidic residues  0

Hydrophobic residues  8

Net charge  8

Boman Index  -8906

Hydrophobicity  -96.67

Aliphatic Index  86.67

Half Life 
  Mammalian: 1.1 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  11000

Absorbance 280nm  647.06

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 32151609

Title  Design of human lactoferricin derived antitumor peptides-activity and specificity against malignant melanoma in 2D and 3D model studies

Doi Not available

Year  2020

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  16503

DRACP is developed by Dr.Zheng's team.