DIM-LF11-322
General Information
DRACP ID DRACP04054
Peptide Name DIM-LF11-322
Sequence PFWRIRIRRPFWRIRIRR
Sequence Length 18
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C122H194N44O19
Absent amino acids ACDEGHKLMNQSTVY
Common amino acids R
Mass 288454
Pl 13.35
Basic residues 8
Acidic residues 0
Hydrophobic residues 8
Net charge 8
Boman Index -8906
Hydrophobicity -96.67
Aliphatic Index 86.67
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 11000
Absorbance 280nm 647.06
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 32151609
Title Design of human lactoferricin derived antitumor peptides-activity and specificity against malignant melanoma in 2D and 3D model studies
Doi Not available
Year 2020
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 16503