R-DIM-P-LF11-334

General Information


DRACP ID  DRACP04055

Peptide Name   R-DIM-P-LF11-334

Sequence  PWRIRIRRPRRIRIWP

Sequence Length  16

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C103H171N39O17

Absent amino acids  ACDEFGHKLMNQSTVY

Common amino acids  R

Mass  249545

Pl  13.28

Basic residues  7

Acidic residues  0

Hydrophobic residues  6

Net charge  7

Boman Index  -8010

Hydrophobicity  -125.63

Aliphatic Index  97.5

Half Life 
  Mammalian: >20 hour
  Yeast: >20 hour
  E.coli: ?

Extinction Coefficient cystines  11000

Absorbance 280nm  733.33

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 32151609

Title  Design of human lactoferricin derived antitumor peptides-activity and specificity against malignant melanoma in 2D and 3D model studies

Doi Not available

Year  2020

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  16504

DRACP is developed by Dr.Zheng's team.