Lactotransferrin (590-619), Lactofungin

General Information


DRACP ID  DRACP04065

Peptide Name   Lactotransferrin (590-619), Lactofungin

Sequence  LLCLDGTRKPVTEAQSCHLAVAPNHAVVSR

Sequence Length  30

UniProt ID  P24627 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C136H229N43O41S2

Absent amino acids  FIMWY

Common amino acids  ALV

Mass  370417

Pl  8.25

Basic residues  5

Acidic residues  2

Hydrophobic residues  12

Net charge  3

Boman Index  -3778

Hydrophobicity  14.33

Aliphatic Index  104

Half Life 
  Mammalian: 5.5 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  125

Absorbance 280nm  4.31

Polar residues  8

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 32690642

Title  Lactoferrin-Derived Peptide Lactofungin Is Potently Synergistic with Amphotericin B

Doi Not available

Year  2020

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  16556

DRACP is developed by Dr.Zheng's team.