Lfcin B (20-25)-Arenicin-3 [G1,12A; Y5N; Y17H], B6N2

General Information


DRACP ID  DRACP04066

Peptide Name   Lfcin B (20-25)-Arenicin-3 [G1,12A; Y5N; Y17H], B6N2

Sequence  RRWQWRAFCWNVCVYRNAVRVCHRRCN

Sequence Length  27

UniProt ID  A0A3F2YLM5 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C154H233N57O33S4

Absent amino acids  DEGIKLMPST

Common amino acids  R

Mass  400308

Pl  11.74

Basic residues  8

Acidic residues  0

Hydrophobic residues  10

Net charge  8

Boman Index  -9983

Hydrophobicity  -72.22

Aliphatic Index  50.37

Half Life 
  Mammalian: 5.5 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  18240

Absorbance 280nm  701.54

Polar residues  8

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 29329001

Title  Improved antibacterial activity of a marine peptide-N2 against intracellular Salmonella typhimurium by conjugating with cell-penetrating peptides-bLFcin6/Tat11

Doi Not available

Year  2018

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  16573

DRACP is developed by Dr.Zheng's team.