Myotoxin II (105-117)[Y3,6W][Y5K,P9W,C11A], PEM-2 [W5K,A9W]
General Information
DRACP ID DRACP04073
Peptide Name Myotoxin II (105-117)[Y3,6W][Y5K,P9W,C11A], PEM-2 [W5K,A9W]
Sequence KKWRKWLKWLAKK
Sequence Length 13
UniProt ID P24605
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C90H143N25O14
Absent amino acids CDEFGHIMNPQSTVY
Common amino acids K
Mass 201351
Pl 12.1
Basic residues 7
Acidic residues 0
Hydrophobic residues 6
Net charge 7
Boman Index -2958
Hydrophobicity -163.08
Aliphatic Index 67.69
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: >10 hour
Extinction Coefficient cystines 16500
Absorbance 280nm 1375
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30447380
Title Repurposing azithromycin and rifampicin against Gram-negative pathogens by combination with peptide potentiators
Doi Not available
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 16784