This work is licensed under a Creative Commons Attribution 4.0 International License.
Aurein-2.2 (1-14)[V10L, G11K, A12L, G14K]
General Information
DRACP ID DRACP04074
Peptide Name Aurein-2.2 (1-14)[V10L, G11K, A12L, G14K]
Sequence GLFDIVKKVLKLLK
Sequence Length 14
UniProt ID P82389
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C79H140N18O17
Absent amino acids ACEHMNPQRSTWY
Common amino acids KL
Mass 184617
Pl 10.8
Basic residues 4
Acidic residues 1
Hydrophobic residues 8
Net charge 3
Boman Index 568
Hydrophobicity 81.43
Aliphatic Index 180.71
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30506920
Title Simulated Molecular Evolution for Anticancer Peptide Design
Doi Not available
Year 2019
Literature 2
Pubmed ID 32936629
Title Morphing of Amphipathic Helices to Explore the Activity and Selectivity of Membranolytic Antimicrobial Peptides
Doi Not available
Year 2020
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 16801
This work is licensed under a Creative Commons Attribution 4.0 International License.