Oncocin (1-11)-MDAP-2 (28-35)[Q19R], OM19R

General Information


DRACP ID  DRACP04087

Peptide Name   Oncocin (1-11)-MDAP-2 (28-35)[Q19R], OM19R

Sequence  VDKPPYLPRPRPIRRPGGR

Sequence Length  19

UniProt ID  A0A2R7WNA0  A0A088N522 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C100H167N35O23

Absent amino acids  ACEFHMNQSTW

Common amino acids  P

Mass  254886

Pl  12.34

Basic residues  6

Acidic residues  1

Hydrophobic residues  3

Net charge  5

Boman Index  -7325

Hydrophobicity  -153.16

Aliphatic Index  56.32

Half Life 
  Mammalian: 1.1 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  1490

Absorbance 280nm  82.78

Polar residues  3

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Design and Characterization of a Novel Hybrid Antimicrobial Peptide OM19R Based on Oncocin and MDAP-2

Doi Not available

Year  2019

Literature 2

Pubmed ID 33129837

Title  Preparation, Characterization and Pharmacokinetic Study of N-Terminal PEGylated D-Form Antimicrobial Peptide OM19r-8

Doi Not available

Year  2020

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  16941

DRACP is developed by Dr.Zheng's team.