Phylloseptin-PV1, PPV1

General Information


DRACP ID  DRACP04090

Peptide Name   Phylloseptin-PV1, PPV1

Sequence  FLSLIPKIAGGIAALVKNL

Sequence Length  19

UniProt ID  Not available

PubChem CID  Not available

Origin  Animalia

Type  Native peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C93H160N22O22

Absent amino acids  CDEHMQRTWY

Common amino acids  L

Mass  225970

Pl  10.81

Basic residues  2

Acidic residues  0

Hydrophobic residues  12

Net charge  2

Boman Index  2763

Hydrophobicity  140

Aliphatic Index  174.74

Half Life 
  Mammalian: 1.4 hour
  Yeast: 3 min
  E.coli: >10 hour

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  4

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 33193152

Title  A Novel Amphibian Antimicrobial Peptide, Phylloseptin-PV1, Exhibits Effective Anti- staphylococcal Activity Without Inducing Either Hepatic or Renal Toxicity in Mice

Doi Not available

Year  2020

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  16974

DRACP is developed by Dr.Zheng's team.