PN-CATH1

General Information


DRACP ID  DRACP04092

Peptide Name   PN-CATH1

Sequence  KKCNFFCKLKKKVKSVGSRNLIGSATHHHRIYRV

Sequence Length  34

UniProt ID  Not available

PubChem CID  Not available

Origin  Animalia

Type  Native peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C178H296N58O42S2

Absent amino acids  DEMPQW

Common amino acids  K

Mass  457358

Pl  11.48

Basic residues  13

Acidic residues  0

Hydrophobic residues  10

Net charge  13

Boman Index  -7977

Hydrophobicity  -61.76

Aliphatic Index  74.41

Half Life 
  Mammalian: 1.9 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  1615

Absorbance 280nm  48.94

Polar residues  11

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 33242568

Title  Identification and characterization of novel bi-functional cathelicidins from the black-spotted frog (Pelophylax nigromaculata) with both anti-infective and antioxidant activities

Doi Not available

Year  2021

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  17030

DRACP is developed by Dr.Zheng's team.