RTH-sh-Buforin

General Information


DRACP ID  DRACP04094

Peptide Name   RTH-sh-Buforin

Sequence  RTHRAGLQFPVGRVHRLLRK

Sequence Length  20

UniProt ID  P55897 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C106H181N41O23

Absent amino acids  CDEIMNSWY

Common amino acids  R

Mass  273694

Pl  13.1

Basic residues  8

Acidic residues  0

Hydrophobic residues  7

Net charge  8

Boman Index  -6807

Hydrophobicity  -75

Aliphatic Index  92.5

Half Life 
  Mammalian: 1 hour
  Yeast: 30 min
  E.coli: >10 hour

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  3

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 25891844

Title  Hybrid peptide ATCUN-sh-Buforin: Influence of the ATCUN charge and stereochemistry on antimicrobial activity

Doi Not available

Year  2015

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  17032

DRACP is developed by Dr.Zheng's team.