This work is licensed under a Creative Commons Attribution 4.0 International License.
CMK
General Information
DRACP ID DRACP04100
Peptide Name CMK
Sequence RVKR
Sequence Length 4
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antiviral
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification C10
C-terminal Modification CMK
Other Modification None
Chiral L
Physicochemical Information
Formula C23H47N11O5
Absent amino acids ACDEFGHILMNPQSTWY
Common amino acids R
Mass 61138
Pl 12.52
Basic residues 3
Acidic residues 0
Hydrophobic residues 1
Net charge 3
Boman Index -3135
Hydrophobicity -217.5
Aliphatic Index 72.5
Half Life
Mammalian: 20 hour
Yeast: 30 min
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 33007239
Title Furin Inhibitors Block SARS-CoV-2 Spike Protein Cleavage to Suppress Virus Production and Cytopathic Effects
Doi Not available
Year 2020
Literature 2
Pubmed ID 31683742
Title Decanoyl-Arg-Val-Lys-Arg-Chloromethylketone: An Antiviral Compound That Acts against Flaviviruses through the Inhibition of Furin-Mediated prM Cleavage
Doi Not available
Year 2019
Literature 3
Pubmed ID 23617302
Title Therapeutic potential of furin inhibitors for the chronic infection of hepatitis B virus
Doi Not available
Year 2013
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 17117
This work is licensed under a Creative Commons Attribution 4.0 International License.