This work is licensed under a Creative Commons Attribution 4.0 International License.
Dhvar4 [K1,6,13R;L3I;L8F;F9K;S10Y;Y14F]
General Information
DRACP ID DRACP04104
Peptide Name Dhvar4 [K1,6,13R;L3I;L8F;F9K;S10Y;Y14F]
Sequence RRIFKRLFKYLRRF
Sequence Length 14
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C96H155N31O16
Absent amino acids ACDEGHMNPQSTVW
Common amino acids R
Mass 223152
Pl 12.69
Basic residues 7
Acidic residues 0
Hydrophobic residues 6
Net charge 7
Boman Index -6214
Hydrophobicity -79.29
Aliphatic Index 83.57
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 1490
Absorbance 280nm 114.62
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 33281761
Title D- and Unnatural Amino Acid Substituted Antimicrobial Peptides With Improved Proteolytic Resistance and Their Proteolytic Degradation Characteristics
Doi Not available
Year 2020
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 17121
This work is licensed under a Creative Commons Attribution 4.0 International License.