Defensin-like peptide 4/DLP4 [K32G], ID13

General Information


DRACP ID  DRACP04120

Peptide Name   Defensin-like peptide 4/DLP4 [K32G], ID13

Sequence  ATCDLLSPFKVGHAACAAHCIARGKRGGWCDGRAVCNCRK

Sequence Length  40

UniProt ID  W5U4X3 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C175H285N61O48S6

Absent amino acids  EMQY

Common amino acids  A

Mass  489980

Pl  8.9

Basic residues  9

Acidic residues  2

Hydrophobic residues  14

Net charge  7

Boman Index  -6250

Hydrophobicity  -4.25

Aliphatic Index  61.25

Half Life 
  Mammalian: 1 hour
  Yeast: 2 min
  E.coli: 2 min

Extinction Coefficient cystines  5875

Absorbance 280nm  150.64

Polar residues  14

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 32506158

Title  Therapeutic potential of a designed CS伪尾 peptide ID13 in Staphylococcus aureus-induced endometritis of mice

Doi Not available

Year  2020

Literature 2

Pubmed ID 32582062

Title  An Enhanced Variant Designed From DLP4 Cationic Peptide Against Staphylococcus aureus CVCC 546

Doi Not available

Year  2020

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  17281

DRACP is developed by Dr.Zheng's team.