Arenicin-3 [G1,12V;C3,20A;Y5N;Y17H], N6 [G1,12V]

General Information


DRACP ID  DRACP04124

Peptide Name   Arenicin-3 [G1,12V;C3,20A;Y5N;Y17H], N6 [G1,12V]

Sequence  VFAWNVCVYRNVVRVCHRRAN

Sequence Length  21

UniProt ID  A0A3F2YLM5 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C113H177N39O26S2

Absent amino acids  DEGIKLMPQST

Common amino acids  V

Mass  291893

Pl  11

Basic residues  5

Acidic residues  0

Hydrophobic residues  10

Net charge  5

Boman Index  -4867

Hydrophobicity  12.86

Aliphatic Index  92.38

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  7115

Absorbance 280nm  355.75

Polar residues  6

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 33348848

Title  Dual Antibacterial Activities and Biofilm Eradication of a Marine Peptide-N6NH 2 and Its Analogs against Multidrug-Resistant Aeromonas veronii

Doi Not available

Year  2020

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  17313

DRACP is developed by Dr.Zheng's team.