Turgencin A (18-27)[K19,20,25,27R;G22,23W,C26K]

General Information


DRACP ID  DRACP04159

Peptide Name   Turgencin A (18-27)[K19,20,25,27R;G22,23W,C26K]

Sequence  GRRPWWWRAR

Sequence Length  10

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C67H95N25O11

Absent amino acids  CDEFHIKLMNQSTVY

Common amino acids  R

Mass  158735

Pl  12.98

Basic residues  4

Acidic residues  0

Hydrophobic residues  4

Net charge  4

Boman Index  -4994

Hydrophobicity  -209

Aliphatic Index  10

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  16500

Absorbance 280nm  1833.33

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 32751755

Title  Antimicrobial Activity of Small Synthetic peptide Peptides Based on the Marine Peptide Turgencin A: Prediction of Antimicrobial Peptide Sequences in a Natural Peptide and Strategy for Optimization of Potency

Doi Not available

Year  2020

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  17822

DRACP is developed by Dr.Zheng's team.