Turgencin A (18-27)[K19,20,25,27R;P21W;G22,23W,C26K]

General Information


DRACP ID  DRACP04160

Peptide Name   Turgencin A (18-27)[K19,20,25,27R;P21W;G22,23W,C26K]

Sequence  GRRWWWWRAR

Sequence Length  10

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C73H98N26O11

Absent amino acids  CDEFHIKLMNPQSTVY

Common amino acids  RW

Mass  167645

Pl  12.98

Basic residues  4

Acidic residues  0

Hydrophobic residues  5

Net charge  4

Boman Index  -4761

Hydrophobicity  -202

Aliphatic Index  10

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  22000

Absorbance 280nm  2444.44

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 32751755

Title  Antimicrobial Activity of Small Synthetic peptide Peptides Based on the Marine Peptide Turgencin A: Prediction of Antimicrobial Peptide Sequences in a Natural Peptide and Strategy for Optimization of Potency

Doi Not available

Year  2020

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  17823

DRACP is developed by Dr.Zheng's team.