Aurein-2.2 (1-14)[V10L, G11R, A12L, G14K]

General Information


DRACP ID  DRACP04165

Peptide Name   Aurein-2.2 (1-14)[V10L, G11R, A12L, G14K]

Sequence  GLFDIVKKVLRLLK

Sequence Length  14

UniProt ID  P82389 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C79H140N20O17

Absent amino acids  ACEHMNPQSTWY

Common amino acids  L

Mass  187418

Pl  11.08

Basic residues  4

Acidic residues  1

Hydrophobic residues  8

Net charge  3

Boman Index  -369

Hydrophobicity  77.14

Aliphatic Index  180.71

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 30506920

Title  Simulated Molecular Evolution for Anticancer Peptide Design

Doi Not available

Year  2019

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  17983

DRACP is developed by Dr.Zheng's team.