This work is licensed under a Creative Commons Attribution 4.0 International License.
Aurein-2.2 (1-14)[V10L, G11R, A12L, G14K]
General Information
DRACP ID DRACP04165
Peptide Name Aurein-2.2 (1-14)[V10L, G11R, A12L, G14K]
Sequence GLFDIVKKVLRLLK
Sequence Length 14
UniProt ID P82389
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C79H140N20O17
Absent amino acids ACEHMNPQSTWY
Common amino acids L
Mass 187418
Pl 11.08
Basic residues 4
Acidic residues 1
Hydrophobic residues 8
Net charge 3
Boman Index -369
Hydrophobicity 77.14
Aliphatic Index 180.71
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30506920
Title Simulated Molecular Evolution for Anticancer Peptide Design
Doi Not available
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 17983
This work is licensed under a Creative Commons Attribution 4.0 International License.