This work is licensed under a Creative Commons Attribution 4.0 International License.
Jelleine-1 [K3R;I4,6L;S5R;H7R]
General Information
DRACP ID DRACP04181
Peptide Name Jelleine-1 [K3R;I4,6L;S5R;H7R]
Sequence PFRLRLRL
Sequence Length 8
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C50H87N17O9
Absent amino acids ACDEGHIKMNQSTVWY
Common amino acids LR
Mass 119538
Pl 12.8
Basic residues 3
Acidic residues 0
Hydrophobic residues 4
Net charge 3
Boman Index -2702
Hydrophobicity -11.25
Aliphatic Index 146.25
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 33878564
Title An optimized analog of antimicrobial peptide Jelleine-1 shows enhanced antimicrobial activity against multidrug resistant P aeruginosa and negligible toxicity in vitro and in vivo
Doi Not available
Year 2021
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 18223
This work is licensed under a Creative Commons Attribution 4.0 International License.