Jelleine-1 [K3R;I4,6L;S5R;H7R]

General Information


DRACP ID  DRACP04181

Peptide Name   Jelleine-1 [K3R;I4,6L;S5R;H7R]

Sequence  PFRLRLRL

Sequence Length  8

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C50H87N17O9

Absent amino acids  ACDEGHIKMNQSTVWY

Common amino acids  LR

Mass  119538

Pl  12.8

Basic residues  3

Acidic residues  0

Hydrophobic residues  4

Net charge  3

Boman Index  -2702

Hydrophobicity  -11.25

Aliphatic Index  146.25

Half Life 
  Mammalian: 1.1 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 33878564

Title  An optimized analog of antimicrobial peptide Jelleine-1 shows enhanced antimicrobial activity against multidrug resistant P aeruginosa and negligible toxicity in vitro and in vivo

Doi Not available

Year  2021

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  18223

DRACP is developed by Dr.Zheng's team.