Jelleine-1 [F2W;K3R;I4,6L;S5R;H7R]
General Information
DRACP ID DRACP04182
Peptide Name Jelleine-1 [F2W;K3R;I4,6L;S5R;H7R]
Sequence PWRLRLRL
Sequence Length 8
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C52H88N18O9
Absent amino acids ACDEFGHIKMNQSTVY
Common amino acids LR
Mass 123442
Pl 12.8
Basic residues 3
Acidic residues 0
Hydrophobic residues 4
Net charge 3
Boman Index -2767
Hydrophobicity -57.5
Aliphatic Index 146.25
Half Life
Mammalian: >20 hour
Yeast: >20 hour
E.coli: ?
Extinction Coefficient cystines 5500
Absorbance 280nm 785.71
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 33878564
Title An optimized analog of antimicrobial peptide Jelleine-1 shows enhanced antimicrobial activity against multidrug resistant P aeruginosa and negligible toxicity in vitro and in vivo
Doi Not available
Year 2021
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 18231