This work is licensed under a Creative Commons Attribution 4.0 International License.
LL-37 (13-32)[I13G,G14I]
General Information
DRACP ID DRACP04183
Peptide Name LL-37 (13-32)[I13G,G14I]
Sequence GIKEFKRIVQRIKDFLRNLV
Sequence Length 20
UniProt ID P49913
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antiviral
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C114H194N34O27
Absent amino acids ACHMPSTWY
Common amino acids IKR
Mass 281209
Pl 11.65
Basic residues 6
Acidic residues 2
Hydrophobic residues 9
Net charge 4
Boman Index -4954
Hydrophobicity -22.5
Aliphatic Index 126.5
Half Life
Mammalian: >20 hour
Yeast: >20 hour
E.coli: ?
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 34959645
Title Structure and Activity of a Selective Antibiofilm Peptide SK-24 Derived from the NMR Structure of Human Cathelicidin LL-37
Doi Not available
Year 2021
Literature 2
Pubmed ID 32252021
Title Engineered Human Cathelicidin Antimicrobial Peptides Inhibit Ebola Virus Infection
Doi Not available
Year 2020
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 18232
This work is licensed under a Creative Commons Attribution 4.0 International License.