G-LL-37 (15-32)/GF-17 [F17TERT BU PHE; I20,24l; F27W; L28l]

General Information


DRACP ID  DRACP04186

Peptide Name   G-LL-37 (15-32)/GF-17 [F17TERT BU PHE; I20,24l; F27W; L28l]

Sequence  GXKRlVQRlKDWlRKLV

Sequence Length  17

UniProt ID  P49913 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  Mix



Physicochemical Information


Formula  C74H121N27O13

Absent amino acids  ACEFHIMNPSTY

Common amino acids  KR

Mass  199251

Pl  12.26

Basic residues  6

Acidic residues  1

Hydrophobic residues  4

Net charge  5

Boman Index  -5940

Hydrophobicity  -125.29

Aliphatic Index  57.06

Half Life 
  /

Extinction Coefficient cystines  5500

Absorbance 280nm  343.75

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 31319057

Title  Modulation of antimicrobial potency of human cathelicidin peptides against the ESKAPE pathogens and in vivo efficacy in a murine catheter-associated biofilm model

Doi Not available

Year  2019

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  18238

DRACP is developed by Dr.Zheng's team.