G-LL-37 (15-32)/GF-17 [F17TERT BU PHE; I20,24l; F27W; L28l]
General Information
DRACP ID DRACP04186
Peptide Name G-LL-37 (15-32)/GF-17 [F17TERT BU PHE; I20,24l; F27W; L28l]
Sequence GXKRlVQRlKDWlRKLV
Sequence Length 17
UniProt ID P49913
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral Mix
Physicochemical Information
Formula C74H121N27O13
Absent amino acids ACEFHIMNPSTY
Common amino acids KR
Mass 199251
Pl 12.26
Basic residues 6
Acidic residues 1
Hydrophobic residues 4
Net charge 5
Boman Index -5940
Hydrophobicity -125.29
Aliphatic Index 57.06
Half Life
/
Extinction Coefficient cystines 5500
Absorbance 280nm 343.75
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 31319057
Title Modulation of antimicrobial potency of human cathelicidin peptides against the ESKAPE pathogens and in vivo efficacy in a murine catheter-associated biofilm model
Doi Not available
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 18238