G-LL-37 (15-32)/GF-17 [F17,27BIP; I20,24l; L28l]

General Information


DRACP ID  DRACP04187

Peptide Name   G-LL-37 (15-32)/GF-17 [F17,27BIP; I20,24l; L28l]

Sequence  GXKRlVQRlKDXlRKLV

Sequence Length  17

UniProt ID  P49913 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  Mix



Physicochemical Information


Formula  C63H109N25O11

Absent amino acids  ACEFHIMNPSTWY

Common amino acids  KR

Mass  189828

Pl  12.26

Basic residues  6

Acidic residues  1

Hydrophobic residues  3

Net charge  5

Boman Index  -6173

Hydrophobicity  -120

Aliphatic Index  57.06

Half Life 
  /

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 31319057

Title  Modulation of antimicrobial potency of human cathelicidin peptides against the ESKAPE pathogens and in vivo efficacy in a murine catheter-associated biofilm model

Doi Not available

Year  2019

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  18291

DRACP is developed by Dr.Zheng's team.