Dermaseptin-TO, Dermaseptin-1

General Information


DRACP ID  DRACP04188

Peptide Name   Dermaseptin-TO, Dermaseptin-1

Sequence  ALWKDLLKNVGIAAGKAALNKVTDMVNQ

Sequence Length  28

UniProt ID  P85523 

PubChem CID  Not available

Origin  Animalia

Type  Native peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C133H225N37O38S

Absent amino acids  CEFHPRSY

Common amino acids  A

Mass  346436

Pl  10.33

Basic residues  4

Acidic residues  2

Hydrophobic residues  14

Net charge  2

Boman Index  -1534

Hydrophobicity  15

Aliphatic Index  118.57

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  5500

Absorbance 280nm  203.7

Polar residues  6

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 33582221

Title  In vitro activities of a novel antimicrobial peptide isolated from phyllomedusa tomopterna

Doi Not available

Year  2021

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  18370

DRACP is developed by Dr.Zheng's team.