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Human beta-defensin-4, hBD4
General Information
DRACP ID DRACP04208
Peptide Name Human beta-defensin-4, hBD4
Sequence EFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRKWDESLLNRTKP
Sequence Length 50
UniProt ID Q8WTQ1
PubChem CID Not available
Origin Animalia
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C254H410N82O74S6
Absent amino acids HMV
Common amino acids R
Mass 686309
Pl 9.13
Basic residues 12
Acidic residues 6
Hydrophobic residues 10
Net charge 6
Boman Index -17104
Hydrophobicity -100.8
Aliphatic Index 50.8
Half Life
Mammalian:
Yeast:
E.coli:
Extinction Coefficient cystines 10345
Absorbance 280nm 211.12
Polar residues 19
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 34025617
Title A Chimeric Cationic Peptide Composed of Human 尾-Defensin 3 and Human 尾-Defensin 4 Exhibits Improved Antibacterial Activity and Salt Resistance
Doi Not available
Year 2021
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 18490
This work is licensed under a Creative Commons Attribution 4.0 International License.