This work is licensed under a Creative Commons Attribution 4.0 International License.
hBD3(1-23)-hBD4(20-28)-hBD3(33-45), H4
General Information
DRACP ID DRACP04209
Peptide Name hBD3(1-23)-hBD4(20-28)-hBD3(33-45), H4
Sequence GIINTLQKYYCRVRGGRCAVLSCRSQEYRIGRCSTRGRKCCRRKK
Sequence Length 45
UniProt ID Q8WTQ1
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C218H378N82O59S6
Absent amino acids DFHMPW
Common amino acids R
Mass 606926
Pl 11.17
Basic residues 14
Acidic residues 1
Hydrophobic residues 8
Net charge 13
Boman Index -16482
Hydrophobicity -84.44
Aliphatic Index 58.44
Half Life
Mammalian: 1 hour
Yeast: 30 min
E.coli: >10 hour
Extinction Coefficient cystines 4845
Absorbance 280nm 110.11
Polar residues 20
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 34025617
Title A Chimeric Cationic Peptide Composed of Human 尾-Defensin 3 and Human 尾-Defensin 4 Exhibits Improved Antibacterial Activity and Salt Resistance
Doi Not available
Year 2021
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 18491
This work is licensed under a Creative Commons Attribution 4.0 International License.