This work is licensed under a Creative Commons Attribution 4.0 International License.
Polymyxin B-12
General Information
DRACP ID DRACP04262
Peptide Name Polymyxin B-12
Sequence TXXXfLXXT
Sequence Length 9
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification C8
C-terminal Modification Free
Other Modification None
Chiral Mix
Physicochemical Information
Formula C14H15N3
Absent amino acids ACDEFGHIKMNPQRSVWY
Common amino acids X
Mass 91816
Pl 6.11
Basic residues 0
Acidic residues 0
Hydrophobic residues 1
Net charge 0
Boman Index -22
Hydrophobicity 26.67
Aliphatic Index 43.33
Half Life
/
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 36708325
Title Discovery of Biologically Optimized Polymyxin Derivatives Facilitated by Peptide Scanning and In Situ Screening Chemistry
Doi Not available
Year 2023
Literature 2
Pubmed ID 26734854
Title Activity and Predicted Nephrotoxicity of Synthetic peptide Antibiotics Based on Polymyxin B
Doi Not available
Year 2016
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 18759
This work is licensed under a Creative Commons Attribution 4.0 International License.