12-(His)4-12

General Information


DRACP ID  DRACP04278

Peptide Name   12-(His)4-12

Sequence  HHHH

Sequence Length  4

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  C12

C-terminal Modification  C12

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C24H30N12O5

Absent amino acids  ACDEFGIKLMNPQRSTVWY

Common amino acids  H

Mass  62028

Pl  7.88

Basic residues  4

Acidic residues  0

Hydrophobic residues  0

Net charge  4

Boman Index  -1864

Hydrophobicity  -320

Aliphatic Index  0

Half Life 
  Mammalian: 1 hour
  Yeast: 2 min
  E.coli: 2 min

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 32193931

Title  Gemini Peptide Amphiphiles with Broad-Spectrum Antimicrobial Activity and Potent Antibiofilm Capacity

Doi Not available

Year  2020

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  18796

DRACP is developed by Dr.Zheng's team.