Cyclo(Val-Gly), Diketopiperazine (VG)

General Information


DRACP ID  DRACP04303

Peptide Name   Cyclo(Val-Gly), Diketopiperazine (VG)

Sequence  VG

Sequence Length  2

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Parasite



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C7H14N2O3

Absent amino acids  ACDEFHIKLMNPQRSTWY

Common amino acids  GV

Mass  19222

Pl  6.11

Basic residues  0

Acidic residues  0

Hydrophobic residues  1

Net charge  0

Boman Index  498

Hydrophobicity  190

Aliphatic Index  145

Half Life 
  Mammalian: 1 hour
  Yeast: 2 min
  E.coli: 2 min

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 18436344

Title  The synthesis and anticancer activity of selected diketopiperazines

Doi Not available

Year  2008

Literature 2

Pubmed ID 23084276

Title  Linear and cyclic dipeptides with antimalarial activity

Doi Not available

Year  2012

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  18854

DRACP is developed by Dr.Zheng's team.