This work is licensed under a Creative Commons Attribution 4.0 International License.
Cyclo(Trp-His), Diketopiperazine (WH)
General Information
DRACP ID DRACP04313
Peptide Name Cyclo(Trp-His), Diketopiperazine (WH)
Sequence WH
Sequence Length 2
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C17H19N5O3
Absent amino acids ACDEFGIKLMNPQRSTVY
Common amino acids HW
Mass 35939
Pl 7.55
Basic residues 1
Acidic residues 0
Hydrophobic residues 1
Net charge 1
Boman Index -233
Hydrophobicity -205
Aliphatic Index 0
Half Life
Mammalian:
Yeast:
E.coli:
Extinction Coefficient cystines 5500
Absorbance 280nm 5500
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 22617493
Title Prenylation at the indole ring leads to a significant increase of cytotoxicity of tryptophan-containing cyclic dipeptides
Doi Not available
Year 2012
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 18871
This work is licensed under a Creative Commons Attribution 4.0 International License.