This work is licensed under a Creative Commons Attribution 4.0 International License.
Cyclo(Pro-Val)
General Information
DRACP ID DRACP04318
Peptide Name Cyclo(Pro-Val)
Sequence PV
Sequence Length 2
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C10H18N2O3
Absent amino acids ACDEFGHIKLMNQRSTWY
Common amino acids PV
Mass 23228
Pl 6.11
Basic residues 0
Acidic residues 0
Hydrophobic residues 1
Net charge 0
Boman Index 404
Hydrophobicity 130
Aliphatic Index 145
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 25821788
Title Cytotoxicity of cyclodipeptides from Pseudomonas aeruginosa PAO1 leads to apoptosis in human cancer cell lines
Doi Not available
Year 2015
Literature 2
Pubmed ID 33924262
Title Antimicrobial and Antibiofilm Activities of the Fungal Metabolites Isolated from the Marine Endophytes Epicoccum nigrum M13 and Alternaria alternata 13A
Doi Not available
Year 2021
Literature 3
Pubmed ID 35142498
Title Cyclo(l-proline-l-serine) Dipeptide Suppresses Seed Borne Fungal Pathogens of Rice: Altered Cellular Membrane Integrity of Fungal Hyphae and Seed Quality Benefits
Doi Not available
Year 2022
Literature 4
Pubmed ID 30270742
Title Chemical constituents from the deep sea-derived Streptomyces xiamenensis MCCC 1A01570 and their effects on RXR伪 transcriptional regulation
Doi Not available
Year 2020
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 18892
This work is licensed under a Creative Commons Attribution 4.0 International License.