Cyclo(His-Tyr)

General Information


DRACP ID  DRACP04329

Peptide Name   Cyclo(His-Tyr)

Sequence  HY

Sequence Length  2

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C15H18N4O4

Absent amino acids  ACDEFGIKLMNPQRSTVW

Common amino acids  HY

Mass  33635

Pl  7.54

Basic residues  1

Acidic residues  0

Hydrophobic residues  0

Net charge  1

Boman Index  -480

Hydrophobicity  -225

Aliphatic Index  0

Half Life 
  Mammalian: 3.5 hour
  Yeast: 10 min
  E.coli: >10 hour

Extinction Coefficient cystines  1490

Absorbance 280nm  1490

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 15324483

Title  An investigation into the biological activity of the selected histidine-containing diketopiperazines cyclo(His-Phe) and cyclo(His-Tyr)

Doi Not available

Year  2004

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  18936

DRACP is developed by Dr.Zheng's team.