Cyclo(His-Gly)

General Information


DRACP ID  DRACP04338

Peptide Name   Cyclo(His-Gly)

Sequence  HG

Sequence Length  2

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C8H12N4O3

Absent amino acids  ACDEFIKLMNPQRSTVWY

Common amino acids  GH

Mass  23023

Pl  7.55

Basic residues  1

Acidic residues  0

Hydrophobic residues  0

Net charge  1

Boman Index  -372

Hydrophobicity  -180

Aliphatic Index  0

Half Life 
  Mammalian: 3.5 hour
  Yeast: 10 min
  E.coli: >10 hour

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 16797105

Title  The biological activity of the histidine-containing diketopiperazines cyclo(His-Ala) and cyclo(His-Gly)

Doi Not available

Year  2006

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  18981

DRACP is developed by Dr.Zheng's team.