Esculentin-2 HYba2

General Information


DRACP ID  DRACP04341

Peptide Name   Esculentin-2 HYba2

Sequence  SILSLFKMGAKALGKTLIKQAGKAGAEYVACKATNQC

Sequence Length  37

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C168H286N46O48S3

Absent amino acids  DHPRW

Common amino acids  A

Mass  445693

Pl  10.3

Basic residues  6

Acidic residues  1

Hydrophobic residues  15

Net charge  5

Boman Index  -1203

Hydrophobicity  20

Aliphatic Index  90

Half Life 
  Mammalian: 1.9 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  1615

Absorbance 280nm  44.86

Polar residues  12

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 31328553

Title  Identification and functional characterisation of Esculentin-2 HYba peptides and their C-terminally amidated analogs from the skin secretion of an endemic frog

Doi Not available

Year  2021

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  18987

DRACP is developed by Dr.Zheng's team.