This work is licensed under a Creative Commons Attribution 4.0 International License.
Dermaseptin t-DPH1 [S4K,A11A,L18K]
General Information
DRACP ID DRACP04345
Peptide Name Dermaseptin t-DPH1 [S4K,A11A,L18K]
Sequence GLWKKIKNVAKAAGKAAKGAL
Sequence Length 21
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C98H171N29O23
Absent amino acids CDEFHMPQRSTY
Common amino acids AK
Mass 248057
Pl 11.5
Basic residues 6
Acidic residues 0
Hydrophobic residues 11
Net charge 6
Boman Index -513
Hydrophobicity -9.05
Aliphatic Index 98.1
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 5500
Absorbance 280nm 275
Polar residues 4
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 34943741
Title Exploration of the Structure-Function Relationships of a Novel Frog Skin Secretion-Derived Bioactive Peptide, t-DPH1, through Use of Rational Design, Cationicity Enhancement and In Vitro Studies
Doi Not available
Year 2021
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 18991
This work is licensed under a Creative Commons Attribution 4.0 International License.