Brevibacillin

General Information


DRACP ID  DRACP04349

Peptide Name   Brevibacillin

Sequence  XLXIIVKVVKYLX

Sequence Length  13

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Native peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  2-OH-ME-C5

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C60H100N12O9

Absent amino acids  ACDEFGHMNPQRSTW

Common amino acids  VX

Mass  167776

Pl  10.25

Basic residues  2

Acidic residues  0

Hydrophobic residues  7

Net charge  2

Boman Index  2056

Hydrophobicity  154.62

Aliphatic Index  186.92

Half Life 
  /

Extinction Coefficient cystines  1490

Absorbance 280nm  124.17

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 34220785

Title  Brevibacillin 2V, a Novel Antimicrobial Lipopeptide With an Exceptionally Low Hemolytic Activity

Doi Not available

Year  2021

Literature 2

Pubmed ID 26921428

Title  Isolation and Structural Elucidation of Brevibacillin, an Antimicrobial Lipopeptide from Brevibacillus laterosporus That Combats Drug-Resistant Gram-Positive Bacteria

Doi Not available

Year  2016

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  18996

DRACP is developed by Dr.Zheng's team.