This work is licensed under a Creative Commons Attribution 4.0 International License.
Actinomycesin AMSIN, Defensin-like Bacteriocin
General Information
DRACP ID DRACP04356
Peptide Name Actinomycesin AMSIN, Defensin-like Bacteriocin
Sequence GFGCPWNAYECDRHCVSKGYTGGNCRGKIRQTCHCY
Sequence Length 36
UniProt ID E7N5J9
PubChem CID Not available
Origin Bacteria
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C171H253N55O50S6
Absent amino acids LM
Common amino acids CG
Mass 469607
Pl 8.38
Basic residues 7
Acidic residues 2
Hydrophobic residues 5
Net charge 5
Boman Index -7909
Hydrophobicity -77.5
Aliphatic Index 21.67
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 10345
Absorbance 280nm 295.57
Polar residues 20
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 34927385
Title Adaptively evolved human oral actinomyces-sourced defensins show therapeutic potential
Doi Not available
Year 2022
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 19007
This work is licensed under a Creative Commons Attribution 4.0 International License.