This work is licensed under a Creative Commons Attribution 4.0 International License.
Lfcin B (20-25)-P- LL-37 KR-12-a4, Lf-KR
General Information
DRACP ID DRACP04364
Peptide Name Lfcin B (20-25)-P- LL-37 KR-12-a4, Lf-KR
Sequence RRWQWRPKRIVKLIKKWLR
Sequence Length 19
UniProt ID P24627
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C126H208N42O21
Absent amino acids ACDEFGHMNSTY
Common amino acids R
Mass 296854
Pl 13.11
Basic residues 9
Acidic residues 0
Hydrophobic residues 8
Net charge 9
Boman Index -7163
Hydrophobicity -132.11
Aliphatic Index 97.37
Half Life
Mammalian: 1.2 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 16500
Absorbance 280nm 916.67
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 35288606
Title A novel hybrid peptide composed of LfcinB6 and KR-12-a4 with enhanced antimicrobial, anti-inflammatory and anti-biofilm activities
Doi Not available
Year 2022
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 19035
This work is licensed under a Creative Commons Attribution 4.0 International License.