Bactenecin-7 (1-23)[P5I,L18Y,P19F,F20M], Bac7PS
General Information
DRACP ID DRACP04397
Peptide Name Bactenecin-7 (1-23)[P5I,L18Y,P19F,F20M], Bac7PS
Sequence RRIRIRPPRLPRPRPRPYFMPRP
Sequence Length 23
UniProt ID P19661
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C135H226N50O25S
Absent amino acids ACDEGHKNQSTVW
Common amino acids R
Mass 337419
Pl 13.04
Basic residues 9
Acidic residues 0
Hydrophobic residues 4
Net charge 9
Boman Index -11433
Hydrophobicity -161.3
Aliphatic Index 50.87
Half Life
Mammalian: 4.4 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 1490
Absorbance 280nm 67.73
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 35578204
Title Optimization of the antimicrobial peptide Bac7 by deep mutational scanning
Doi Not available
Year 2022
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 19372