This work is licensed under a Creative Commons Attribution 4.0 International License.
BotrAMP14
General Information
DRACP ID DRACP04400
Peptide Name BotrAMP14
Sequence KRWKKFFRKVIKFF
Sequence Length 14
UniProt ID U5KJC9
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C100H152N26O15
Absent amino acids ACDEGHLMNPQSTY
Common amino acids K
Mass 219051
Pl 12.57
Basic residues 7
Acidic residues 0
Hydrophobic residues 7
Net charge 7
Boman Index -3438
Hydrophobicity -67.86
Aliphatic Index 48.57
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 5500
Absorbance 280nm 423.08
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 32499582
Title Physicochemical-guided design of cathelicidin-derived peptides generates membrane active variants with therapeutic potential
Doi Not available
Year 2020
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 19513
This work is licensed under a Creative Commons Attribution 4.0 International License.