CrotAMP14

General Information


DRACP ID  DRACP04401

Peptide Name   CrotAMP14

Sequence  KRLKKIFKKMIKIF

Sequence Length  14

UniProt ID  U5KJM4 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C89H157N23O15S

Absent amino acids  ACDEGHNPQSTVWY

Common amino acids  K

Mass  205349

Pl  12.1

Basic residues  7

Acidic residues  0

Hydrophobic residues  6

Net charge  7

Boman Index  -2023

Hydrophobicity  -22.14

Aliphatic Index  111.43

Half Life 
  Mammalian: 1.3 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 32499582

Title  Physicochemical-guided design of cathelicidin-derived peptides generates membrane active variants with therapeutic potential

Doi Not available

Year  2020

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  19514

DRACP is developed by Dr.Zheng's team.