Cecropin A (1-7)+Melittin (2-9)[I2L]-C, CAMA-CPP

General Information


DRACP ID  DRACP04432

Peptide Name   Cecropin A (1-7)+Melittin (2-9)[I2L]-C, CAMA-CPP

Sequence  KWKLFKKLGAVLKVLC

Sequence Length  16

UniProt ID  P01507 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C92H156N22O17S

Absent amino acids  DEHIMNPQRSTY

Common amino acids  K

Mass  214220

Pl  10.98

Basic residues  5

Acidic residues  0

Hydrophobic residues  9

Net charge  5

Boman Index  935

Hydrophobicity  61.88

Aliphatic Index  140

Half Life 
  Mammalian: 1.3 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  5500

Absorbance 280nm  366.67

Polar residues  2

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 34528343

Title  Antibacterial efficacy of in-house designed cell-penetrating peptide against multi-drug resistant strains of Salmonella Enteritidis and Salmonella Typhimurium

Doi Not available

Year  2022

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  19779

DRACP is developed by Dr.Zheng's team.