[Lfcin B (20-25)]2[Q4,10L;R6L]

General Information


DRACP ID  DRACP04435

Peptide Name   [Lfcin B (20-25)]2[Q4,10L;R6L]

Sequence  RRWLWLRRWLWR

Sequence Length  12

UniProt ID  P24627 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C92H135N31O13

Absent amino acids  ACDEFGHIKMNPQSTVY

Common amino acids  R

Mass  207966

Pl  13.1

Basic residues  5

Acidic residues  0

Hydrophobic residues  7

Net charge  5

Boman Index  -5052

Hydrophobicity  -122.5

Aliphatic Index  97.5

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  22000

Absorbance 280nm  2000

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 36009954

Title  Design and Evaluation of Short Bovine Lactoferrin-Derived Antimicrobial Peptides against Multidrug-Resistant聽Enterococcus faecium

Doi Not available

Year  2022

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  19825

DRACP is developed by Dr.Zheng's team.