Latarcin-3a, Ltc-3a

General Information


DRACP ID  DRACP04461

Peptide Name   Latarcin-3a, Ltc-3a

Sequence  SWKSMAKKLKEYMEKLKQRA

Sequence Length  20

UniProt ID  Q1ELU3 

PubChem CID  Not available

Origin  Animalia

Type  Native peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C111H187N31O29S2

Absent amino acids  CDFGHINPTV

Common amino acids  K

Mass  282309

Pl  10.84

Basic residues  7

Acidic residues  2

Hydrophobic residues  5

Net charge  5

Boman Index  -5383

Hydrophobicity  -136

Aliphatic Index  49

Half Life 
  Mammalian: 1.9 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  6990

Absorbance 280nm  367.89

Polar residues  3

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 36212827

Title  First generation of multifunctional peptides derived from latarcin-3a from聽Lachesana tarabaevi聽spider toxin

Doi Not available

Year  2022

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  20021

DRACP is developed by Dr.Zheng's team.