General Information
DRACP ID DRACP04465
Peptide Name
Sequence rGDFV
Sequence Length 5
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral Mix
Physicochemical Information
Formula C20H26N4O6
Absent amino acids ACEHIKLMNPQRSTWY
Common amino acids DFGV
Mass 48998
Pl 3.75
Basic residues 0
Acidic residues 1
Hydrophobic residues 2
Net charge -1
Boman Index -76
Hydrophobicity 62
Aliphatic Index 58
Half Life
/
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 1718779
Title Arg-Gly-Asp constrained within cyclic pentapeptides Strong and selective inhibitors of cell adhesion to vitronectin and laminin fragment P1
Doi Not available
Year 1991
Literature 2
Pubmed ID 21269250
Title Cilengitide: the first anti-angiogenic small molecule drug candidate design, synthesis and clinical evaluation
Doi Not available
Year 2010
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 20025