This work is licensed under a Creative Commons Attribution 4.0 International License.
General Information
DRACP ID DRACP04469
Peptide Name
Sequence GRGDS
Sequence Length 5
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C17H30N8O9
Absent amino acids ACEFHIKLMNPQTVWY
Common amino acids G
Mass 56200
Pl 6.34
Basic residues 1
Acidic residues 1
Hydrophobic residues 0
Net charge 0
Boman Index -2516
Hydrophobicity -192
Aliphatic Index 0
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 3
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 1718779
Title Arg-Gly-Asp constrained within cyclic pentapeptides Strong and selective inhibitors of cell adhesion to vitronectin and laminin fragment P1
Doi Not available
Year 1991
Literature 2
Pubmed ID 21269250
Title Cilengitide: the first anti-angiogenic small molecule drug candidate design, synthesis and clinical evaluation
Doi Not available
Year 2010
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 20030
This work is licensed under a Creative Commons Attribution 4.0 International License.