Samoamide A
General Information
DRACP ID DRACP04516
Peptide Name Samoamide A
Sequence LVFPIFPP
Sequence Length 8
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C50H72N8O9
Absent amino acids ACDEGHKMNQRSTWY
Common amino acids P
Mass 105420
Pl 6.11
Basic residues 0
Acidic residues 0
Hydrophobic residues 5
Net charge 0
Boman Index 1984
Hydrophobicity 166.25
Aliphatic Index 133.75
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Synthesis and antitumor activity of cyclic octapeptide, samoamide A, and its derivatives
Doi Not available
Year 2019
Literature 2
Pubmed ID 28055219
Title Integrating Molecular Networking and Biological Assays To Target the Isolation of a Cytotoxic Cyclic Octapeptide, Samoamide A, from an American Samoan Marine Cyanobacterium
Doi Not available
Year 2017
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 20238