Samoamide A

General Information


DRACP ID  DRACP04516

Peptide Name   Samoamide A

Sequence  LVFPIFPP

Sequence Length  8

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Native peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C50H72N8O9

Absent amino acids  ACDEGHKMNQRSTWY

Common amino acids  P

Mass  105420

Pl  6.11

Basic residues  0

Acidic residues  0

Hydrophobic residues  5

Net charge  0

Boman Index  1984

Hydrophobicity  166.25

Aliphatic Index  133.75

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Synthesis and antitumor activity of cyclic octapeptide, samoamide A, and its derivatives

Doi Not available

Year  2019

Literature 2

Pubmed ID 28055219

Title  Integrating Molecular Networking and Biological Assays To Target the Isolation of a Cytotoxic Cyclic Octapeptide, Samoamide A, from an American Samoan Marine Cyanobacterium

Doi Not available

Year  2017

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  20238

DRACP is developed by Dr.Zheng's team.