Ocellatin-3N [A18K]

General Information


DRACP ID  DRACP04522

Peptide Name   Ocellatin-3N [A18K]

Sequence  GIFDVLKNLAKGVITSLKS

Sequence Length  19

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C92H159N23O26

Absent amino acids  CEHMPQRWY

Common amino acids  KL

Mass  232467

Pl  10.51

Basic residues  3

Acidic residues  1

Hydrophobic residues  9

Net charge  2

Boman Index  -203

Hydrophobicity  61.05

Aliphatic Index  138.42

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  6

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 36426386

Title  Antimicrobial, cytotoxic, and insulin-releasing activities of the amphibian host-defense peptide ocellatin-3N and its L-lysine-substituted analogs

Doi Not available

Year  2022

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  20348

DRACP is developed by Dr.Zheng's team.