General Information


DRACP ID  DRACP04524

Peptide Name  

Sequence  CLLFVY

Sequence Length  6

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C38H56N6O8S

Absent amino acids  ADEGHIKMNPQRSTW

Common amino acids  L

Mass  84633

Pl  5.91

Basic residues  0

Acidic residues  0

Hydrophobic residues  4

Net charge  0

Boman Index  1800

Hydrophobicity  263.33

Aliphatic Index  178.33

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  1490

Absorbance 280nm  298

Polar residues  2

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 23796364

Title  A cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells

Doi Not available

Year  2013

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  20455

DRACP is developed by Dr.Zheng's team.